Leaves yellow comb callisia fragrans (Lindl.) Known as an herb has many good effects to human health. Many studies have demonstrated the strategic parts of the tree yellow with many compounds bioactive, typical polyphenol compounds. In this study, the feasibility of the polyphenol compounds extracted from leaf gold comb with supercritical CO2 fluid with co-solvents are considered. Influence of pressure, temperature, flow total, as well as the ethanol concentration (% w / w) to the total polyphenol content and antioxidant activity of the extract is high in survey extraction. High gold fronds were extracted under conditions combining the results of the survey: 200 bar pressure, temperature 450C, the total volume of 20 g / min, the concentration of ethanol 14% (w / w), with results integrated total polyphenol content, total flavonoid content and antioxidant activity is approximately equal the total polyphenol content and antioxidant activity of the extract by means of Soxhlet high with ethylacetate solvent. Therefore, the applicability of the compounds extracted bioactive gold comb from leaves by supercritical CO2 fluid can make.
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