Sigma-Aldrich - T3758 Page 1 of 7SI

Sigma-Aldrich - T3758 Page 1 of 7
SIGMA-ALDRICH sigma-aldrich.com
SAFETY DATA SHEET
according to Regulation (EC) No. 1907/2006
Version 5.0 Revision Date 21.11.2012
Print Date 16.11.2014
GENERIC EU MSDS - NO COUNTRY SPECIFIC DATA - NO OEL DATA
1. IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING
1.1 Product identifiers
Product name : Thioglycolic acid
Product Number : T3758
Brand : Sigma-Aldrich
Index-No. : 607-090-00-6
CAS-No. : 68-11-1
1.2 Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances
1.3 Details of the supplier of the safety data sheet
Company : Sigma-Aldrich Pte Ltd
1 Science Park Road
#02-14 The Capricorn
Singapore Science Park Road II
SINGAPORE 117528
SINGAPORE
Telephone : [phone]
Fax : [phone]
1.4 Emergency telephone number
Emergency Phone # : [phone]
2. HAZARDS IDENTIFICATION
2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008 [EU-GHS/CLP]
Acute toxicity, Oral (Category 3)
Acute toxicity, Inhalation (Category 1)
Acute toxicity, Dermal (Category 3)
Skin corrosion (Category 1B)
Classification according to EU Directives 67/548/EEC or 1999/45/EC
Causes burns. Toxic by inhalation, in contact with skin and if swallowed.
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008 [CLP]
Pictogram
Signal word Danger
Hazard statement(s)
H301 Toxic if swallowed.
H311 Toxic in contact with skin.
H314 Causes severe skin burns and eye damage.
H330 Fatal if inhaled.
Precautionary statement(s)
P260 Do not breathe dust/ fume/ gas/ mist/ vapours/ spray.
Sigma-Aldrich - T3758 Page 2 of 7
P280 Wear protective gloves/ protective clothing/ eye protection/ face
protection.
P284 Wear respiratory protection.
P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/
physician.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing.
P310 Immediately call a POISON CENTER or doctor/ physician.
Supplemental Hazard
Statements
none
According to European Directive 67/548/EEC as amended.
Hazard symbol(s)
R-phrase(s)
R23/24/25 Toxic by inhalation, in contact with skin and if swallowed.
R34 Causes burns.
S-phrase(s)
S25 Avoid contact with eyes.
S27 Take off immediately all contaminated clothing.
S28 After contact with skin, wash immediately with plenty of soap and water.
S45 In case of accident or if you feel unwell, seek medical advice immediately
(show the label where possible).
2.3 Other hazards
Vesicant., Stench., Rapidly absorbed through skin.
3. COMPOSITION/INFORMATION ON INGREDIENTS
3.1 Substances
Formula : C2H4O2S
Molecular Weight : 92,12 g/mol
Component Concentration
Mercaptoacetic acid
CAS-No.
EC-No.
Index-No.
68-11-1
200-677-4
607-090-00-6
-
4. FIRST AID MEASURES
4.1 Description of first aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact
Take off contaminated clothing and shoes immediately. Wash off with soap and plenty of water. Take
victim immediately to hospital. Consult a physician.
In case of eye contact
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed
Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with
water. Consult a physician.
Sigma-Aldrich - T3758 Page 3 of 7
4.2 Most important symptoms and effects, both acute and delayed
Material is extremely destructive to tissue of the mucous membranes and upper respiratory tract, eyes, and
skin., Cough, Shortness of breath, Headache, Nausea
4.3 Indication of any immediate medical attention and special treatment needed
no data available
5. FIREFIGHTING MEASURES
5.1 Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture
Carbon oxides, Sulphur oxides
5.3 Advice for firefighters
Wear self contained breathing apparatus for fire fighting if necessary.
5.4 Further information
no data available
6. ACCIDENTAL RELEASE MEASURES
6.1 Personal precautions, protective equipment and emergency procedures
Wear respiratory protection. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Evacuate
personnel to safe areas.
6.2 Environmental precautions
Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the
environment must be avoided.
6.3 Methods and materials for containment and cleaning up
Soak up with inert absorbent material and dispose of as hazardous waste. Keep in suitable, closed
containers for disposal.
6.4 Reference to other sections
For disposal see section 13.
7. HANDLING AND STORAGE
7.1 Precautions for safe handling
Avoid contact with skin and eyes. Avoid inhalation of vapour or mist.
7.2 Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are
opened must be carefully resealed and kept upright to prevent leakage.
Recommended storage temperature: -20 °C
7.3 Specific end uses
no data available
8. EXPOSURE CONTROLS/PERSONAL PROTECTION
8.1 Control parameters
Components with workplace control parameters
8.2 Exposure controls
Appropriate engineering controls
Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling
the product.
Sigma-Aldrich - T3758 Page 4 of 7
Personal protective equipment
Eye/face protection
Tightly fitting safety goggles. Faceshield (8-inch minimum). Use equipment for eye protection
tested and approved under appropriate government standards such as NIOSH (US) or EN
166(EU).
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique
(without touching glove's outer surface) to avoid skin contact with this product. Dispose of
contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.
The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and
the standard EN 374 derived from it.
Full contact
Material: butyl-rubber
Minimum layer thickness: 0,3 mm
Break through time: > 480 min
Material tested:Butoject® (Aldrich Z677647, Size M)
Splash protection
Material: Nature latex/chloroprene
Minimum layer thickness: 0,6 mm
Break through time: > 30 min
Material tested:Lapren® (Aldrich Z677558, Size M)
data source: KCL GmbH, D-36124 Eichenzell, phone [phone], e-mail [e-mail],
test method: EN374
If used in solution, or mixed with other substances, and under conditions which differ from EN 374,
contact the supplier of the CE approved gloves. This recommendation is advisory only and must
be evaluated by an Industrial Hygienist familiar with the specific situation of anticipated use by our
customers. It should not be construed as offering an approval for any specific use scenario.
Body Protection
Complete suit protecting against chemicals, The type of protective equipment must be selected
according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection
Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator
with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup
to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air
respirator. Use respirators and components tested and approved under appropriate government
standards such as NIOSH (US) or CEN (EU).
9. PHYSICAL AND CHEMICAL PROPERTIES
9.1 Information on basic physical and chemical properties
a) Appearance Form: liquid
b) Odour no data available
c) Odour Threshold no data available
d) pH 1,5 at 10 g/l at 20 °C
e) Melting point/freezing
point
Melting point/range: -16 °C
f) Initial boiling point and
boiling range
96 °C at 7 hPa
g) Flash point 130 °C - closed cup
h) Evaporation rate no data available
i) Flammability (solid, gas) no data available
Sigma-Aldrich - T3758 Page 5 of 7
j) Upper/lower
flammability or
explosive limits
Lower explosion limit: 5,9 %(V)
k) Vapour pressure 0,5 hPa at 25 °C
l) Vapour density 3,18 - (Air = 1.0)
m) Relative density 1,325 g/cm3
n) Water solubility completely miscible
o) Partition coefficient: noctanol/
water
log Pow: 0,059
p) Autoignition
temperature
no data available
q) Decomposition
temperature
no data available
r) Viscosity no data available
s) Explosive properties no data available
t) Oxidizing properties no data available
9.2 Other safety information
no data available
10. STABILITY AND REACTIVITY
10.1 Reactivity
no data available
10.2 Chemical stability
no data available
10.3 Possibility of hazardous reactions
no data available
10.4 Conditions to avoid
no data available
10.5 Incompatible materials
Strong oxidizing agents, Strong acids
10.6 Hazardous decomposition products
Other decomposition products - no data available
11. TOXICOLOGICAL INFORMATION
11.1 Information on toxicological effects
Acute toxicity
LD50 Oral - rat - 114 mg/kg
LC50 Inhalation - rat - 4 h - 21 mg/m3
LD50 Dermal - rabbit - 848 mg/kg
Skin corrosion/irritation
no data available
Serious eye damage/eye irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Sigma-Aldrich - T3758 Page 6 of 7
Carcinogenicity
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as
probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
no data available
Specific target organ toxicity - single exposure
no data available
Specific target organ toxicity - repeated exposure
no dat

Kết quả (Anh) 2:

Sigma-Aldrich - T3758 Page 1 of 7
Sigma-Aldrich sigma-aldrich.com
SAFETY DATA SHEET
theo Regulation (EC) No. 1907/2006
Version 5.0 Revision Date 11.21.2012
Print Date 11/16/2014
MSDS EU Generics - NO COUNTRY SPECIFIC DATA - NO DATA OEL
1. IDENTIFICATION OF THE Substance / MIXTURE AND OF THE COMPANY / Undertaking
1.1 Product identifiers
Product name: Thioglycolic Acid
Product Number: T3758
Brand: Sigma-Aldrich
Index-No. : 607-090-00-6
CAS-No. : 68-11-1
1.2 Relevant Identified sử of the substance or mixture and sử advised với
Identified sử: Laboratory chemicals, Manufacture of substances
1.3 Details of the supplier of the safety data sheet
Company: Sigma-Aldrich Pte Ltd
1 Science Park Road
# 02-14 The Capricorn
Singapore Science Park II Road
SINGAPORE 117528
SINGAPORE
Telephone: [phone]
Fax: [phone]
1.4 Emergency telephone number
Emergency Phone #: [phone]
2. Hazards IDENTIFICATION
2.1 Classification of the substance or mixture
theo Classification Regulation (EC) No 1272/2008 [EU-GHS / CLP]
Acute toxicity, Oral (Category 3)
Acute toxicity, inhalation (Category 1)
Acute toxicity, Dermal (Category 3 )
Skin corrosion (Category 1B)
Classification theo EU Directives 67/548 / EEC or 1999/45 / EC
Causes burns. Toxic by inhalation, in contact with skin and if swallowed.
2.2 Label elements
theo Labelling Regulation (EC) No 1272/2008 [CLP]
pictogram
Danger Signal word
Hazard statement (s)
H301 Toxic if swallowed.
H311 Toxic in contact with skin.
H314 Causes Severe skin burns and eye damage.
H330 Fatal if inhaled.
precautionary statement (s)
P260 Do not breathe dust / fume / gas / mist / vapours / spray.
Sigma-Aldrich - T3758 Page 2 of 7
P280 Wear protective gloves / protective clothing / eye protection / face
protection.
Respiratory protection Wear P284.
P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor /
physician.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for vài minutes. Remove
contact lenses, if present and easy to do. Continue rinsing.
P310 Immediately call a POISON CENTER or doctor / physician.
Supplemental Hazard
Statements
none
theo European Directive 67/548 / EEC as amended.
Hazard symbol (s)
R-phrase (s)
R23 / 24/25 Toxic by inhalation, in contact with skin and if swallowed.
R34 Causes burns.
S-phrase (s)
S25 Avoid contact with eyes.
S27 Take off all contaminated clothing ngay.
S28 After contact with skin, wash ngay with Plenty of soap and water.
S45 In case of Accident or if you feel unwell, seek medical Advice IMMEDIATELY
(show the label where thể).
2.3 Other hazards
Vesicant., stench., Rapidly Absorbed through skin.
3. Composition / INFORMATION ON INGREDIENTS
Substances 3.1
Formula: C2H4O2S
Molecular Weight: 92.12 g / mol
Component Concentration
Mercaptoacetic acid
CAS-No.
EC-No.
Index-No.
68-11-1
200-677-4
607-090-00 -6
-
4. FIRST AID Measures
4.1 Description of First Aid Measures
General Advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
If Breathed in, move person Into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact
Take off contaminated clothing and shoes ngay. Wash off with soap and Plenty of Water. Take
victim to hospital ngay. Consult a physician.
In case of eye contact
Rinse thoroughly with Plenty of water for 15 minutes at nhất and consult a physician.
If swallowed
Do NOT induce vomiting. Never give anything by mouth to safety unconscious person. Rinse mouth with
water. Consult a physician.
Sigma-Aldrich - T3758 Page 3 of 7
4.2 Most Important Symptoms and effects, acute and delayed cả
Material is extremely destructive to tissue of the mucous membranes and upper Respiratory tract, eyes, and
skin., Cough, shortness of breath , Headache, Nausea
4.3 Indication of any immediate medical Attention and special treatment needed
no data available
5. Firefighting Measures
5.1 Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Special hazards arising from the substance or mixture
Carbon oxides, sulfur oxides
5.3 Advice for firefighters
Wear self contained breathing apparatus for fire fighting if cần.
5.4 Further information
no data available
6. Accidental RELEASE Measures
6.1 Personal precautions, protective equipment and emergency Procedures
Respiratory protection Wear. Avoid breathing vapors, mist or gas. Ensure adequate Ventilation. Evacuate
personnel to safe which areas.
6.2 Environmental precautions
Prevent Leakage or spillage if safe Further loud by comparison. Do not let product enter Drains. Discharge Into the
environment Phải avoided.
6.3 Methods and materials for containment and cleaning up
Soak up with inert absorbent material and dispose of as hazardous waste. Keep in Suitable, closed
containers for disposal.
6.4 Reference to other points sections
For disposal see section 13.
7. AND STORAGE Handling
Precautions for safe handling 7.1
Avoid contact with skin and eyes. Avoid inhalation of mist or Vapour.
7.2 Conditions for safe storage, gồm any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Mà containers are
opened Phải resealed and kept upright Carefully to Prevent Leakage.
Recommended storage temperature: -20 ° C
7.3 Specific end sử
no data available
8. EXPOSURE CONTROLS / PERSONAL PROTECTION
8.1 Control parameters
Components with workplace control parameters
8.2 Exposure controls
Appropriate engineering controls
Avoid contact with skin, eyes and clothing. Wash hands after handling the before breaks and ngay
the product.
Sigma-Aldrich - T3758 Page 4 of 7
Personal protective equipment:
Eye / face protection
Tightly fitting safety goggles. Faceshield (8-inch minimum). Use equipment for eye protection
Tested and Approved under the appropriate Government như Standards NIOSH (US) or EN
166 (EU).
Skin protection
Handle with gloves. Gloves Phải Inspected prior to use. Use proper glove removal Technique
(without glove's outer surface Touching) to Avoid skin contact with this product. Dispose of
contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.
The selected protective gloves have to Satisfy the specifications of EU Directive 89/686 / EEC and
the standard EN 374 derived from it.
Full contact
Material : butyl-rubber
Minimum layer thickness: 0.3 mm
Break through time:> 480 min
Material Tested: Butoject® (Aldrich Z677647, Size M)
Splash protection
Material: Nature latex / chloroprene
Minimum layer thickness: 0.6 mm
Break through time :> 30 min
Material Tested: Lapren® (Aldrich Z677558, Size M)
data source: KCL GmbH, D-36124 Eichenzell, phone [phone], e-mail [e-mail],
test method: EN374
If USED ​​in solution, or mixed with substances other points, and under conditionsEND_SPAN mà khác from EN 374,
contact the supplier of the gloves CE Approved. This recommendation is advisory only and phải
Be Evaluated by police Industrial Hygienist familiar with the specific Situation of anticipated use by our
customers table. It shouldnt be construed as offering safety approvals for any specific use scenario.
Body Protection
Suit Complete Protecting Against chemicals, The type of protective equipment selected Phải
theo Concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection
Where-to-risk assessment shows air-purifying respirators are the appropriate use a full-face respirator
with multi-purpose Combination (US) or type ABEK (EN 14387) respirator cartridges as a backup
to engineering controls. If the respirator is the sole nghĩa of protection, use a full-face supplied air
respirator. Use respirators and components under the appropriate Government Tested and Approved
Standards như NIOSH (US) or CEN (EU).
9. PHYSICAL AND CHEMICAL PROPERTIES
9.1 Information on basic physical and chemical properties
a) Appearance Form: liquid
b) Odour no data available
c) Odour Threshold no data available
d) pH 1.5 at 10 g / l at 20 ° C
e) Melting point / freezing
point
Melting point / range: -16 ° C
f) Initial boiling point and
boiling range
96 ° C at 7 hPa
g) Flash point 130 ° C - closed cup
h) Evaporation rate no data available
i) Flammability (solid, gas ) no data available
Sigma-Aldrich - T3758 Page 5 of 7
j) Upper / lower
flammability or
explosive limits
Lower explosion limit: 5.9% (V)
k) Vapour pressure of 0.5 hPa at 25 ° C
l) Vapour density 3 18 - (Air = 1.0)
m) Relative density 1.325 g / cm3
n) Water solubility completely miscible
o) Partition coefficient: noctanol /
water
log Pow: 0.059
p) Autoignition
temperature
no data available
q) Decomposition
temperature
no data available
r) no data available viscosity
s) Explosive properties no data available
t) Oxidizing properties no data available
9.2 Other safety information
available no data
10. AND REACTIVITY Stability
10.1 Reactivity
no data available
10.2 Chemical Stability
no data available
10.3 Possibility of hazardous Reactions
no data available
10.4 Conditions to Avoid
no data available
materials 10.5 tương thích
Strong oxidizing agents, Strong acids
10.6 Hazardous decomposition products
Other decomposition products - no data available
11 . TOXICOLOGICAL INFORMATION
11.1 Information on toxicological effects
Acute toxicity
LD50 Oral - rat - 114 mg / kg
LC50 inhalation - rat - 4 h - 21 mg / m3
Dermal LD50 - rabbit - 848 mg / kg
Skin corrosion / irritation
no data available
Serious eye damage / eye irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Sigma-Aldrich - T3758 Page 6 of 7
carcinogenicity
IARC: No component of this product present at levels greater than or equal to 0.1% is Identified as
probable, Possible human carcinogen by IARC or nhận.
Reproductive toxicity
no data available
Specific target organ toxicity - single exposure
no data available
Specific target organ toxicity - repeated exposure
no dat