General variables
Fever (> 38.3 ° C)
Hypothermia (core temperature <36 ° C)
Heart rate> 90 / min-1 or more above the normal charcoal two sd value for age
Tachypnea
Altered mental status
Significant edema or positive fluid balance (> 20mL / kg over 24hr)
Hyperglycemia (plasma glucose> 140 mg / dL or 7.7 mmol / L) in the Absence of diabetes
Inflammatory variables
leukocytosis may be absent (WBC count> 12,000 uL-1)
Leukopenia (WBC count <4000 uL-1)
Normal WBC count with greater than 10% immature forms
Plasma C-reactive protein hơn above the normal two sd value
Plasma procalcitonin hơn above the normal two sd value
Hemodynamic variables
Arterial hypotension (SBP <90 mm Hg, MAP <70 mm Hg, or an SBP Decrease> 40mm Hg in adults or less charcoal two sd
below normal for age)
Organ dysfunction variables
Arterial hypoxemia (PaO 2 / FiO2 <300)
Acute oliguria (urine output <0.5ml / kg / hr for 2 hrs at nhất despite adequate fluid Resuscitation)
Creatinine tăng> 0.5 mg / dL or 44.2 μmol / L
coagulation abnormalities (INR> 1.5 or aPTT> 60 s)
Ileus (absent Bowel sounds)
Thrombocytopenia (platelet count <100,000 uL-1)
Hyperbilirubinemia (plasma total bilirubin> 4mg / dL or 70 μmol / L)
Tissue perfusion variables
Hyperlactatemia (> 1 mmol / L)
Decreased capillary refill or mottling
đang được dịch, vui lòng đợi..