Clinical trials have demonstrated that the treatment of mild to moderate hypertension can reduce 30-43% the risk of stroke and heart attack by 15%. In most studies, the non-compliance was considered to occur when the patient does not use ≥ 80% of lower blood pressure according to their prescriptions. Rate of 80% is used as a cutting point to distinguish compliance and non-compliance. Non-compliance with treatment is the most important cause leading to uncontrolled blood pressure and only 20 to 80% of patients treated for hypertension is regarded as "the good compliance" [39].
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