Bryla (1996), a nurse researcher, review the documentation that addressed the relationship between stress and the development of breast cancer and the effects of the immune system. She used the published articles, book chapters, books, and workbooks from nursing and medicine as the source. The study showed a positive relationship exists between the stress and the development of breast cancer, although the exact mechanism is unclear. Most researchers tend to describe women who develop breast cancer or who have experienced disease progression or both as there are certain personality traits and are on in response to emotional stress. These characteristics include inhibiting emotions, depression, avoidance of conflict, coping style pressure, uncertainty, Extrovert, and inhibit sex. Inability to manage anger (so-called anger in), sadomasochism, aggression, and hostility (wearing a mask with a mere façade) all seem to contribute to the risk of breast cancer (Bahnson, 1981; Cooper, Cooper, & Faragher, 1989). It was suggested that the immune system can mediate the physiological effects of stress on breast cancer (Hulka & Moorman, 2001; Peled, Siboni-Samocha, Carmil, & Shoham-Vardi, 2008). Bryla pointed out the problem of isolating an individual's perception of stress from foreign factors often co-exist with it (for example, fear and depression).
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