The anticoagulants and inhibitors of platelet aggregation: There have been cases of bleeding or prolonged prothrombin time in patients concomitantly pentoxifylline with anticoagulants, or inhibitors of platelet aggregation. Need testing identified more frequent prothrombin time for the patient to be treated simultaneously with pentoxifylline and oral anticoagulants, such as warfarin. Must perform periodic tests for signs of bleeding, including pentoxifylline solution has identified risk factors likely to cause bleeding complications (eg recent surgery, stomach ulcers - Duodenal, brain hemorrhage or retinal hemorrhage).
The other medicines: interactions clinically important not happen pentoxifylline in patients with beta blockers and - adrenergic, cardiac glycosides, diuretics, drugs diabetes or antiarrhythmic drugs. Although interactions clinically important not happened until now, still need to monitor systemic blood pressure periodically in patients concomitantly pentoxifylline and antihypertensive drugs, and if specified, should reduced dose antihypertensive drugs because in some individual patients using pentoxifylline had a slight decrease in blood pressure.
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